Foundations of plasmas for medical applications

نویسندگان

چکیده

Abstract Plasma medicine refers to the application of nonequilibrium plasmas at approximately body temperature, for therapeutic purposes. Nonequilibrium are weakly ionized gases which contain charged and neutral species electric fields, emit radiation, particularly in visible ultraviolet range. Medically-relevant cold atmospheric pressure plasma (CAP) sources devices usually dielectric barrier discharges jets. diagnostic methods modelling approaches used characterize densities fluxes active their interaction with surrounding matter. In addition direct onto living tissue, treatment liquids like water or physiological saline by a CAP source is performed order study specific biological activities. A basic understanding between bio-interfaces essential follow effects. Charged species, metastable other atomic molecular reactive first produced main ignition transported discharge afterglow finally be exposed targets. Contact these liquid-dominated generates secondary oxygen nitrogen (ROS, RNS). Both ROS RNS possess strong oxidative properties can trigger redox-related signalling pathways cells leading various impacts relevance. Dependent on intensity exposure, redox balance influenced way that eustress leads stimulation cellular processes distress cell death. Currently, clinical realized mainly wound healing. The use cancer (i.e. oncology) currently emerging field research. Future perspectives challenges directed towards control optimization devices, broaden establish its medical applications, open up new plasma-based therapies medicine.

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ژورنال

عنوان ژورنال: Plasma Sources Science and Technology

سال: 2022

ISSN: ['1361-6595', '0963-0252']

DOI: https://doi.org/10.1088/1361-6595/ac604f